Glossary Term

LOE

Loss of Exclusivity (LOE) is the point at which a medicine's patent or regulatory data protection expires, enabling generic or biosimilar market entry and typically triggering significant price erosion.

Illustration representing LOE
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Related terms
LCM NCE NME
Further reading
Wikipedia: Patent Cliff EY: How to Navigate LOS Browse the HEOR resource database

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Media Kit · Q2 2026

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