🧭 Early Access · Live now · HEOR Fundamentals

Feeling frustrated that your market access and HEOR colleagues always seem to know more than you?

In a few weeks, HEOR Fundamentals gives you the structured understanding of health economics & outcomes research that usually takes years on the job to piece together. From first principles to real market access decisions.

The course is live now. Enrol today and start with the modules already released. New modules are added as they are released. The early-access price of £1,150 ends on 31 December 2026.

Willingness‑to‑pay £20,000/QALY
Cost‑effective —
The world's largest HEOR channelCreated by the host of the most-followed health economics channel on YouTube.
Pharma and consulting insiderBuilt from years working both sides of the table, in pharma and in consulting. Practice, not theory.
Trusted to train teamsRecently delivered bespoke in-house HEOR training for WEP Clinical.

🪞 Let's be honest…

Does this sound like you?

You're good at your job. Really good, actually! But HEOR was never taught to you in one structured way. You picked it up in pieces, between deadlines, or from people who assumed you already knew…

  • I hear HEOR terminology in every meeting, but I don't fully understand it.
  • I know what a QALY is… roughly… but I couldn't confidently explain it.
  • I work with HEOR evidence, but nobody ever taught me the fundamentals.
  • I understand pieces of it, but not how everything actually connects.
  • I learned this in bits and pieces, never as one clear framework.
  • When a payer says no, I can't always explain why, or what would change it.

👽 You're not alone

You're not behind. You were just never taught this.

Every week, professionals across pharma, biotech and consulting say the same thing: they're expected to understand the health economics behind major decisions, without ever having been taught it.

"From my experience, not a lot of good free resources other than YouTube, courtesy of gurus like Mirko. For paid resources, you can try the ISPOR short courses, or online certificate or masters programs."

— 🐄 MooMooMilk, in the community Discord server
The comment that sparked this course. Thanks, MooMooMilk.

"Mirko delivered a highly engaging and thought provoking training and we thoroughly enjoyed it."

Tracey Tingle · Director, Commercial Strategy, Market Access, WEP Clinical

"Mirko has developed such an in-depth understanding of HEOR that he is able to break down complex theories into bite size snippets to help those with less experience in HEOR understand the issues well… He will always be my go to for complex matters related to HEOR."

From Pharmacist→Now National Market Access
Adrian Coleman · National Market Access Manager

🔭 Imagine 12 weeks from now…

You could walk into any HEOR conversation and follow every word

  • You explain a QALY, an ICER and a willingness-to-pay threshold clearly, to a colleague or to a payer.
  • You read a cost-effectiveness model and know exactly what question it's answering.
  • Economic models like Markov, partitioned-survival, patient-level simulation and cure-fraction models don't sound intimidating anymore.
  • You understand how NICE, AMNOG and US payers each decide what gets reimbursed, and why.
  • You know where AI helps in HEOR (and where it doesn't), without the hype, and without feeling left behind.
  • You could take the hot seat at a NICE committee meeting as the company representative, and hold your own.
  • You see the whole journey, from clinical evidence to economic model to market access decision, as one connected picture.
  • You stop nodding along and start contributing.

🧱 Introducing

HEOR Fundamentals

The fastest, most structured way to build a real, lasting understanding of health economics and outcomes research. It is designed for busy professionals in market access, pricing and HEOR who want to finally understand it from the inside.

Format
Self-paced video

Focused lessons of about 7–20 minutes, 15+ hours in total when the course is complete. Learn on your schedule, revisit anytime.

Plus live access
Small-cohort Q&A

Live question-and-answer sessions with Mirko in a small group. Ask anything about your real work.

Built to stick
Explain → apply → recall

Every concept is taught simply, applied through a worked example, then revisited so it actually lands.

🧪 Built to actually stick

Designed on the science of how people really learn

Most courses are easy to watch and easy to forget. This one is deliberately built around what decades of cognitive-science research show works, so it sticks long after the last lesson.

🧠

Retrieval, not re-watching

Module 1 opens with a mind map of what HEOR is. Then your first task is to redraw it from memory. Recalling beats re-reading for lasting retention.Roediger & Karpicke, 2006

🌙

Spaced out, with sleep in between

It's built to be taken across sessions, not binged. Spacing your study and sleeping between modules consolidates memory far better than cramming.Cepeda et al., 2006 · Diekelmann & Born, 2010

🪨

A little struggle, by design

Some exercises make you do the slightly harder, less convenient thing. That "desirable difficulty" feels slower now but builds understanding that lasts.Bjork & Bjork, 2011

🗣️

If you can explain it simply, you get it

After each concept you're prompted to explain it in plain language, as if teaching a colleague. This is the Feynman technique, backed by the self-explanation effect.Chi et al., 1994

These are robust, well-replicated findings. The course is built around them. They are a deliberate design for retention, not a promise of results.

🗣️ What you'll be able to do

From self-doubt to fully confident

  • Confidently discuss HEOR concepts in meetings and reviews
  • Interpret HEOR outputs: ICER tables, the cost-effectiveness plane, sensitivity analyses
  • Explain why cost-effectiveness drives reimbursement decisions
  • Read decision trees, Markov and partitioned-survival models without fear
  • Understand the UK, German and US payer systems and how they differ
  • See how every part of HEOR connects, end to end
  • Explain where HEOR fits across a cross-functional pharma organisation, and turn sophisticated technical ideas into language any team understands

Curious how fluent you are right now? Open the Pharma Glossary, hit Random, and see how many terms you could explain without peeking at the definition.

🗺️ The curriculum

Twelve modules, one connected path

From first principles to a full end-to-end case study, structured the way you wish someone had taught you on day one.

🧭 The 12 modules match the 12 areas of my free HEOR Roadmap. Score yourself in 10 minutes and see which modules will help you most. Take the Roadmap →

Start here

Module 0

How This Course Works

How you learn, how each module is built, and how to get help. You also score yourself on the HEOR Roadmap inside the portal before you begin.

Part I: Foundations

Module 01

Foundations of HEOR

What HEOR is, why every yes to a treatment costs something else, where cost-effectiveness thresholds come from, how health systems pay, and where HEOR fits in the product lifecycle.

Module 02

The Language of HEOR

The vocabulary of epidemiology, outcomes, costs, evidence and value. You learn to use the words with confidence, so you never get lost in translation.

Module 03

Statistics & Data Analysis

Effect measures, survival curves, confidence and uncertainty, comparing treatments, and why correlation is not causation.

Part II: Evidence & Modelling

Module 04

Evidence & Data Sources

Clinical trials, the evidence hierarchy and real-world evidence: where HEOR evidence comes from, and how much weight each source carries.

Module 05

Economic Modelling

Everything you need to understand a health economic model: the main model types, how a model is structured, how it handles uncertainty, and how to read and challenge the results. Step-by-step build tutorials are in my free YouTube playlists.

Part III: Access & Pricing

Module 06

Market Access Strategy

Value dossiers, payer archetypes and market access schemes: how evidence turns into an access strategy.

Module 07

Pricing & Contracting

List price versus net price, rebates and value-based contracts.

Part IV: Major Markets

Module 08 · UK, Germany & EU

Three Systems: NICE, AMNOG & JCA

How NICE in England, AMNOG in Germany and the new EU Joint Clinical Assessment decide on new medicines, and how they differ.

Module 09 · United States

The US System

Payers, pharmacy benefit managers (PBMs) and the policy layer that shapes US access and pricing.

Part V: Skills for Impact

Module 10

Influence, Communication & Selling

Being right is the easy part. Learn to explain HEOR to people who do not speak it, and to win support for your evidence.

Module 11

Artificial Intelligence in HEOR

Prompting, automation, and where AI fails. Practical skills with no hype and no technical background needed.

Part VI: Integration

Module 12 · Capstone

Integration & Mastery

One product, end to end, across three markets. You finish with an asset of your own that shows what you can do.

This gives you a clear picture of what the course covers. The course is in early access: new modules are added as they are released, and some details may still change.

🎁 Plus a bonus module and a recap. The bonus module is not on the agenda for a reason. You find out what is in it when you get there. The final recap brings the main takeaways of the whole course together in one place.
What's in the box?! What's in the f***ing box?!

📦 What's included

  • Self-paced video lessons across 12 core modules, plus an orientation module, a bonus module and a recap
  • Worked examples: calculate a QALY, interpret an ICER, pick the right model
  • Knowledge checks after each module
  • Downloadable resources: terminology cheat sheet, QALY worksheet, country-comparison framework
  • Live small-cohort Q&A sessions
  • Certificate of completion

✂️ Deliberately out of scope (so it stays focused)

  • Building models from scratch in Excel or R (already covered free in my Excel and R modelling playlists)
  • Advanced statistics and network meta-analysis methodology
  • Survival extrapolation methods and utility elicitation
  • TreeAge / VBA tutorials and dossier-writing mechanics
  • Country-specific procedural edge cases

Got a question, or a topic you'd love to see?

The course is in early access, so your input shapes what comes next. Email me with any questions about the programme, or suggestions for topics you'd like covered. I read and reply to every message.

Email me your questions

🪪 Who it's for

Built for market access, pricing and HEOR professionals

If your work touches HEOR, even from the edges, this course is built for you. The people who benefit most come from roles like:

🔑Market access
💷Pricing & reimbursement
📊HEOR & outcomes research
🌍Real-world evidence
🩺Medical affairs
🤝Medical science liaisons
📋Regulatory affairs
📈Commercial & marketing
⚙️Clinical operations
🧮Biostatistics
💊Ex-pharmacists
🏥Ex-nurses & clinicians
🧭Consultants & analysts
✍️Medical writers

This is for you if…

  • You're early-to-mid career in market access, pricing, HEOR, medical affairs or outcomes research
  • You've moved in from an adjacent field: clinical, nursing, pharmacy, biostatistics or consulting
  • You're exposed to HEOR but never had the fundamentals taught in one place
  • You want to feel calm and in control in economics conversations

This is not for you if…

  • You're an experienced health economist building models day to day
  • You want a deep technical course in R, survival analysis or NMA methodology
  • You're looking for a tick-box certificate rather than real understanding

🎙️ Nice to meet you

Mirko von Hein

Hi, I'm Mirko 👋

HEOR Fundamentals is the distillation of my 10+ years working in HEOR, on both the pharma and the consulting side, and my journey of creating 100+ free educational videos watched by professionals worldwide, in one structured course. Think of it as beautifully aged whiskey. 🥃

I'm a health economist and HEOR consultant, and I run the largest HEOR channel in the world. I've spent more than a decade on both sides of the table, inside pharma and in consulting. I have worked on cost-effectiveness modelling, market access strategy and reimbursement evidence. Today I teach the field to a global professional audience.

Here's the thing: almost nobody is handed HEOR as a structured whole. I learned it the way most people do, in fragments, on real projects, filling gaps as I went. I've watched talented colleagues from clinical, pricing and consulting backgrounds carry the same uncertainty: they work in market access and HEOR every day, but were never actually taught the fundamentals. HEOR Fundamentals is the course I wish I'd had on day one.

  • Host of the world's largest HEOR channel on YouTube (100+ free explainers) and The Pharma Perspective podcast
  • 10+ years working in HEOR, across pharma and consulting
  • Several peer-reviewed publications (ORCID & Google Scholar)
  • M.Sc. Health Economics & Healthcare Management, University of Hamburg, HCHE
  • Author of the 2026 HEOR Salary & Career Report
  • Delivered bespoke in-house HEOR training for WEP Clinical

🦋 A quick gut-check

Are you ready to finally understand how HEOR actually works?

  • You're tired of half-understanding the conversations you're in
  • You'd rather learn it properly once than keep googling it forever
  • You want a structured path, not another pile of scattered tutorials
  • You're ready to go from exposed to fluent in weeks, not years

🪺 Early access · live now

Start today at the early-access price

The course is live and open for enrolment. You start straight away with every module released so far, and you get each new module as it arrives. Early-access learners get direct access to me and help shape the rest of the curriculum. On 1 January 2027 the price rises to £1,400.

Early-access price ends in
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£1,400 £1,150 Early-access price, exclusive of VAT · employer-funded · invoice & PO available · lifetime access
Early-access price · ends 31 Dec
  • All 12 core modules, plus orientation, bonus and recap. Instant access to every released lesson, and every new module as it arrives, forever
  • Live small-cohort Q&A sessions with Mirko
  • Worked examples, worksheets & cheat sheets
  • Knowledge checks after every module
  • Certificate of completion (LinkedIn-ready)
  • £250 below the standard price, locked in when you enrol
Every new module is included. You pay once at the early-access price. Each module released after you enrol is added to your account at no extra cost. Your access starts as soon as you enrol. At checkout you ask for immediate access and confirm that you lose the 14-day right to cancel once access begins, so the course is non-refundable from that point. Your statutory rights always apply if anything is faulty or not as described. Full terms & refund policy →

🧾 Funding & employer sponsorship

Most professionals get this funded by their employer

HEOR Fundamentals is a professional-development investment, and it's built to be easy for your manager or L&D team to approve.

Invoices & POs accepted

Pay by invoice or purchase order in GBP, EUR or USD. Card is not the only option. VAT invoice provided for your finance team.

Team seats

Sending three or more colleagues? Ask about team rates, and about bringing it in-house for your whole team.

A ready-made manager pitch

Don't write the email yourself. Copy our ready-to-send justification below, or download it as a one-page PDF.

Or download the one-page justification (PDF) →

🧩 For teams

Training a whole team? I also deliver bespoke in-house programmes

Beyond the open course, I build tailored HEOR and market access training for pharma and consulting teams, shaped around your therapy areas, your markets and your people's level. Most recently, an in-house programme for WEP Clinical.

Mirko von Hein presenting to the audience during the WEP Clinical in-house HEOR training
Mirko von Hein presenting at the WEP Clinical HEOR training session
Mirko von Hein with the WEP Clinical team after the training

In-house HEOR training, delivered for the WEP Clinical team.

🧐 Questions

Frequently asked

Can my employer pay for this?
Yes. Most participants are employer-funded. You can pay by invoice or purchase order, and we provide a VAT invoice for your finance team. Waitlist members also get a one-pager to forward to a manager or L&D contact to make the approval ask simple.
Do I need a technical or modelling background?
No. HEOR Fundamentals is built for professionals who work around health economics: market access, pricing, medical affairs, consulting, or career-switchers from clinical and other fields. It explains every concept from first principles. It deliberately does not teach you to build models in Excel or R.
Is the course accredited?
You'll receive a certificate of completion you can add to LinkedIn and submit for your professional-development records. The course is not yet formally CPD-accredited. That is planned once the full course is released. The curriculum maps to the core competencies the field expects.
Can I still join? When does it start?
Yes. The course is live now, and you can enrol at any time. You start straight away with every module released so far. You get each new module as soon as it is released. When complete, the course has more than 15 hours of focused video lessons, plus live Q&A sessions you can join when they run. The early-access price of £1,150 ends on 31 December 2026.
Can I take the course at my own pace?
Yes. The core course is fully self-paced: short lessons you take whenever suits you, with lifetime access so you can revisit anytime. The only scheduled element is the live small-cohort Q&A sessions, and those are recorded if you can't make them.
Is there a refund policy?
Yes. Your access starts as soon as you enrol. At checkout you ask for immediate access and confirm that you lose the 14-day right to cancel once access begins. From that point the course is non-refundable. Your statutory rights always apply if anything is faulty or not as described. See the full terms.
What does signing up for updates commit me to?
Nothing. There's no payment. You get occasional emails about the course and new modules, and you can enrol whenever you're ready. Note that the early-access price of £1,150 ends on 31 December 2026.
How is this different from your free YouTube videos?
The videos are great introductions to individual topics. HEOR Fundamentals is the complete, structured path: every concept in order, with worked examples, knowledge checks, country deep-dives and an end-to-end case study, so it all connects instead of staying in fragments.

🐌 What's the cost of waiting?

Every month you put it off is another month of half-following the conversations you're in, second-guessing HEOR vocabulary, and missing the chance to contribute where it counts. The people who move ahead & get promoted aren't smarter. They just stopped piecing it together and learned the fundamentals properly. Don't be a slow slug, you're too bright for that!

Enrol now and start today

🎟️ Not ready to enrol?

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Still deciding? Leave your details and stay in the loop: new-module updates, no payment now, and you can enrol whenever you're ready. (Ready now? Enrol here.)

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HEOR Fundamentals · early access live now

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